Aric Gregson M.D.
Assistant Clinical Professor of Medicine
Cellular Immunology of Host-Pathogen Interactions in Solid Organ Transplantation 
Dr. Gregson developed an interest in host-pathogen interactions and translational research while working overseas during during residency and fellowship. After completing his residency training in Internal Medicine at Harbor-UCLA, Dr. Gregson pursued Infectious Diseases training at the University of Maryland. While at the University of Maryland's Center for Vaccine Development he trained as a clinical vaccinologist, running a domestic phase 1 malaria vaccine trial and serving as a co-investigator on two separate phase 1b malaria vaccine trials in Bandiagara, Mali. Dr. Gregson also completed a study to test the hypothesis that antimalarial treatment enhances the spread of drug resistance through the induction and selection of gametocytes carrying resistance-conferring mutations in Bancoumana, Mali. After completion of his Vaccinology Fellowship Dr. Gregson worked with PATH's Malaria Vaccine Initiative (MVI) as the Chief Scientific and Technical Consultant for the RTS,S Malaria Vaccine Project.
His current research focuses on the cellular immune response to infection and allorejection following solid organ transplantation. Ongoing projects include examining the role of regulatory cells, Treg and dendritic cells, in chronic lung allograft rejection (BOS) and developing ultrasensitive assays for the detection of allorejection in solid organ transplantation. Dr. Gregson is a consultant on the Transplant Infectious Diseases Service.
Selected Recent Publications:
Sokolove PE, Lee BS, Krawczyk JA, Banos PT, Gregson AG, Boyce DM, Lewis RJ. Implementation of an Emergency Department Triage Procedure for the Detection and Isolation of Patients at High Risk for Having Pulmonary Tuberculosis. Annals of Emergency Medicine 35(4):327-36, April 2000. doi:10.1016/S0196-0644(00)70050-3
Gregson AG, Edelman RA. Dengue Virus Infections. Pediatric Infectious Disease Journal 22(2):179-181, February 2003.
Gregson AG, Edelman RA. Does Antigen Overload Exist?. Immunology Allergy Clinics of North America Vaccines in the 21st Century, 23(3):649-664, November 2003.
Djimde A, Toure AM, Gregson A, Beavogui A, Sangare CO, Dao A, Traore Z, Maiga H, Fofana B, Coulibaly B, Tekete M, Sacko A, Ouologuem D, Niare O, Wele M, Plowe CV, Doumbo O. Sulfadoxine-Pyrimethamine treatment reduces malaria transmission in a setting of high Sulfadoxine-Pyrimethamine efficacy of Mali. ASTMH 53rd Annual Meeting, 2004.
Gregson AG, Mackowiak PA. Pathogenesis of Fever. In: Infectious Diseases, Second Edition, Cohen J, Powderly WG (ed.), Elsevier Limited, Philadelphia, 2004, p 853-859.
Gregson AG, Plowe CV. Mechanisms of Resistance of Malaria Parasites to Antifolates. Pharmacological Reviews. 57(1):118-145, March 2005.
Thera MA, Doumbo OK, Coulibali D, et. al. Safety and Allele-Specific Immunogenicity of a Malaria Vaccine in Malian Adults: Results of a Phase I Randomized Trial. PLoS Clinical Trials. 2006 Nov 24; 1(7):e34. doi:10.1371/journal.pctr.0010034
Thera MA, Doumbo OK, Coulibali D, et. al. Safety and Immunogenicity of an AMA-1 Malaria Vaccine in Malian Adults: Results of a Phase I Randomized Trial. PLoS ONE 2008 Jan 23; 3(1):e:1465. doi:10.1371/journal.pone.0001465
Gregson AL, Nardin E, Oliveira G, Othoro C, Calvo-Calle M, Birkett A, Sarpotdar P, Edelman R. Phase I trial of Malariavax, a recombinant hepatitis B virus core particle containing repeat and T cell epitopes of the \emph{Plasmodium falciparum} circumsporozoite protein. PLoS ONE 2008 Feb 6; 3(2):e1556. doi:10.1371/journal.pone.0001556
Gregson AL, Hoji A, Saggar R, Ross DJ, Kubak BM, Jamieson BD, Weigt SS, Lynch III JP, Ardehali A, Belperio JA, Yang OO. Bronchoalveolar immunologic profile of acute human lung transplant allograft rejection. Transplantation 2008 Apr 15; 85(7):1056--1059. doi:10.1097/TP.0b013e318169bd85
Gregson AL. Book Review of Communicable Disease Control in Emergencies: A Field Manual. Annals of Internal Medicine 2007 Apr 3; 146(7):544.
Weigt SS, Elashoff RM, Keane MP, Strieter RM, Huang C, Gomperts BN, Xue YY, Zisman DA, Ardehali A, Gregson AL, Kubak B, Fishbein MC, Saggar R, Ross DJ, Lynch III JP, Belperio JA. Altered Levels of CC Chemokines during Pulmonary CMV Predict Mortality and Mortality Due to BOS Post-Lung Transplantation. American Journal of Transplantation 2008 July; 8(7):1512--1522. doi:10.1111/j.1600-6143.2008.02280.x